The 2024 Duke's Mayo Classic will pit ranked teams against each other, as No. 14 Tennessee faces No. 24 NC State on Saturday night in Charlotte. Tennessee opened the season with a 69-3 win over Chattanooga, easily covering the 38.5-point spread. NC State failed to cover the 32-point spread in its opener, but it still picked up a 38-21 win over Western Carolina.  

Kickoff is scheduled for 7:30 p.m. ET at Bank of America Stadium. The Vols are 9-point favorites in the latest NC State vs. Tennessee odds via SportsLine consensus, while the over/under for total points scored is 60. (See up-to-date odds for every game on our college football odds page.)

Before making any Tennessee vs. NC State picks, you need to see the college football predictions and betting advice from SportsLine's proven computer model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks. Anyone who has followed it has seen strong returns.

The model knows that Tennessee freshman quarterback Nico Iamaleava lived up to the hype in Week 1, completing 22 of 28 passes for 313 yards and three touchdowns despite sitting out the entire second half. It marked a school record for passing yards in one half. Chattanooga, which debuted at No. 8 in the FCS preseason poll, did not enter Tennessee territory until its first drive of the second half. 

The model also knows that NC State scored 21 points in the fourth quarter of its opener against Western Carolina to put the game away. Sophomore wide receiver Kevin Concepcion caught nine passes for 121 yards and three touchdowns, while senior running back Jordan Waters rushed for 123 yards and two scores. The Wolfpack played on Thursday night in Week 1, so they have extra rest under their belt heading into this game. 

For Saturday, the model has set its sights on Tennessee vs. North Carolina State. We can tell you the model is leaning Under the total, projecting the teams to combine for 54 points. It also says one side of the spread hits in nearly 60% of simulations!

Who wins NC State vs. Tennessee, and which side of the spread hits nearly 60% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over Saturday, all from the model that's returned more than $2k on its top-rated CFB picks against the spread!